The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 18, 2020

Filed:

Jun. 29, 2016
Applicant:

Sekisui Chemical Co., Ltd., Osaka, Osaka, JP;

Inventors:

Takayuki Akamine, Osaka, JP;

Kazushi Itou, Osaka, JP;

Saori Tone, Osaka, JP;

Yoshiko Abe, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 31/445 (2006.01); A61K 31/53 (2006.01); A61K 9/10 (2006.01); A61K 38/00 (2006.01); A61K 9/06 (2006.01); A61K 9/50 (2006.01); A61K 47/44 (2017.01); A61K 47/14 (2017.01);
U.S. Cl.
CPC ...
A61K 9/0014 (2013.01); A61K 9/06 (2013.01); A61K 9/10 (2013.01); A61K 9/5015 (2013.01); A61K 31/445 (2013.01); A61K 31/53 (2013.01); A61K 38/00 (2013.01); A61K 47/14 (2013.01); A61K 47/44 (2013.01);
Abstract

The present invention provides a core-shell structure having high skin permeability. The core-shell structure includes a core portion containing a hydrophilic drug having a molecular weight of 400 or more; and a shell portion containing a surfactant, and the core portion is a solid, the hydrophilic drug has a water-octanol partition coefficient of −3 or more and 6 or less, the surfactant has an alkyl group or an alkenyl group having 10 to 20 carbon atoms, and a mass ratio between the hydrophilic drug and the surfactant (hydrophilic drug:surfactant) is 1:5 to 1:20.


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