The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2020
Filed:
Apr. 28, 2017
Roche Diagnostics Operations, Inc., Indianapolis, IN (US);
Roberto Latini, Milan, IT;
Serge Masson, Monza, IT;
Dirk Block, Bichl, DE;
Christian Zaugg, Rheinfelden, CH;
Thomas Dieterle, Freiburg, DE;
Edelgard Kaiser, Hünenberg See, CH;
Johann Karl, Peissenberg, DE;
Vinzent Rolny, Munich, DE;
Ursula-Henrike Wienhues-Thelen, Krailling, DE;
Roche Diagnostics Operations, Inc., Indianapolis, IN (US);
Abstract
Described is a method for predicting the risk of a subject of rapidly progressing to chronic heart failure and/or of hospitalization due to chronic heart failure and/or death. The method is based on the determination of at least one biomarker selected from B-type natriuretic peptide (BNP) or N-terminal pro B-type natriuretic peptide (NT-proBNP), IGFBP7 (IGF binding protein 7), a cardiac Troponin, soluble ST2 (sST2), FGF-23 (Fibroblast Growth Factor 23), and Growth Differentiation Factor 15 (GDF-15), in a sample of a subject along with the assessment of the presence or absence of (i) abnormal midwall fractional shortening or (ii) left ventricular hypertrophy.