The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 11, 2020

Filed:

Feb. 24, 2016
Applicants:

Trustees of Boston University, Boston, MA (US);

Ontario Institute for Cancer Research Mars Centre, Toronto, CA;

Inventors:

Tony Edward Godfrey, Chestnut Hill, MA (US);

Anders Torbjoern Staahlberg, Kaallered, SE;

Paul Krzyzanowski, Toronto, CA;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/34 (2006.01); C12N 15/10 (2006.01); C12Q 1/6806 (2018.01); C12Q 1/6855 (2018.01); C12Q 1/6874 (2018.01);
U.S. Cl.
CPC ...
C12N 15/1065 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/6855 (2013.01); C12Q 1/6874 (2013.01);
Abstract

Described herein are approaches for the improved detection, identification, and/or quantification of target nucleic acids. These approaches provide a means of detecting, identifying, and/or quantifying rare target nucleic acid molecules, including DNA and RNA molecules, from the same sample, and in the same reaction, by using 'hairpin barcode primers,' as the term is defined herein, to incorporate unique barcodes into target nucleic acids in a PCR pre-amplification step.


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