The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2020
Filed:
Jul. 21, 2014
Applicant:
Wuhan Yzy Biopharma Co., Ltd., Wuhan, CN;
Inventors:
Pengfei Zhou, Wuhan, CN;
Tao Wang, Wuhan, CN;
Liu Hu, Wuhan, CN;
Mi Huang, Wuhan, CN;
Lijuan Fang, Wuhan, CN;
Yang Liu, Wuhan, CN;
Assignee:
Wuhan YZY Biopharma Co., Ltd., Wuhan, CN;
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/32 (2006.01); C07K 16/28 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/32 (2013.01); A61P 35/00 (2018.01); C07K 16/2809 (2013.01); C07K 2317/31 (2013.01); C07K 2317/73 (2013.01); C07K 2317/92 (2013.01);
Abstract
Provided are compositions comprising a MSBODY and a cytotoxic immune cell (e.g., Cytokine-induced killer cell) to form Armed Activated CIK cells (ACCs), wherein the MSBODY comprising a first antigen binding moiety that has specificity for a tumor antigen, and a second antigen binding moiety that binds to the cell. Provided are also methods preparing a composition comprising a MSBODY and a cytotoxic immune cell, and methods for treating patients with CIK cells armed with bispecific antibodies.