The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2020
Filed:
Jun. 26, 2017
Applicant:
Novimmune SA, Geneva, CH;
Inventors:
Cristina de Min, Geneva, CH;
Limin Shang, Geneva, CH;
Emmanuel Monnet, Geneva, CH;
Greg Elson, Collonges sous Saleve, FR;
Eric Hatterer, Geneva, CH;
Assignee:
NovImmune SA, Geneva, CH;
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 38/00 (2006.01); C07K 16/28 (2006.01); G01N 33/564 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2896 (2013.01); G01N 33/564 (2013.01); A61K 2039/505 (2013.01); C07K 2317/76 (2013.01); G01N 2440/18 (2013.01); G01N 2800/102 (2013.01);
Abstract
This invention relates generally to methods and compositions for diagnosing and treating disorders associated with elevated levels of Toll-like Receptor 4 (TLR4) ligands and other biomarkers. The invention also relates to methods of treating, delaying the progression of, or otherwise ameliorating a symptom of a disorder associated with elevated levels of TLR4 ligands and other biomarkers using agents that interfere with or otherwise antagonize TLR4 signaling, including neutralizing anti-TLR4 antibodies.