The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2020
Filed:
Apr. 19, 2017
Innate Tumor Immunity, Inc., Princeton, NJ (US);
Gary D. Glick, Ann Arbor, MI (US);
Shomir Ghosh, Brookline, MA (US);
William R. Roush, Jupiter, FL (US);
Edward James Olhava, Newton, MA (US);
Innate Tumor Immunity, Inc., Princeton, NJ (US);
Abstract
This disclosure features compounds of Formula I, or a pharmaceutically acceptable salt thereof: in which R, R, R, and Rare as defined herein. These compounds are modulators of NLRP3, which are useful, e.g., for treating a condition, disease or disorder in which a decrease in NLRP3 activity (e.g., a condition, disease or disorder associated with repressed or impaired NLRP3 signaling) contributes to the pathology and/or symptoms and/or progression of the condition, disease or disorder (e.g., cancer) in a subject (e.g., a human). This disclosure also features compositions as well as other methods of using and making the same.