The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2020
Filed:
Jan. 25, 2019
Applicant:
Sci Pharmtech, Inc., Taoyuan, TW;
Inventors:
Heng-Yen Wang, Taoyuan, TW;
Chen-Yi Kao, Taoyuan, TW;
Assignee:
SCI Pharmtech, Inc., Taoyuan, TW;
Primary Examiner:
Int. Cl.
CPC ...
C07D 451/02 (2006.01);
U.S. Cl.
CPC ...
C07D 451/02 (2013.01);
Abstract
Provided is a method for preparing a tropane derivative, maraviroc, including reacting a compound of formula (II) with a compound of formula (I), wherein the compound of formula (II) is prepared by the steps of acetylation of a compound of formula (III), activation and substitution of a compound of formula (IV) by a chlorination agent, cyclization of a compound of formula (V), and debenzylation of a compound of formula (VI) by hydrogenation. Hence, the present disclosure provides a method for preparing maraviroc with good yield and simple operation.