The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2020
Filed:
Feb. 14, 2019
Applicant:
Lycera Corporation, Ann Arbor, MI (US);
Inventors:
Thomas D. Aicher, Ann Arbor, MI (US);
Fernando Padilla, Ann Arbor, MI (US);
Donald J. Skalitzky, Saline, MI (US);
Peter L. Toogood, Ann Arbor, MI (US);
Chad A. VanHuis, Hartland, MI (US);
Assignee:
Lycera Corporation, Ann Arbor, MI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07F 9/6558 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01); C07F 9/65583 (2013.01);
Abstract
The invention provides indazolyl thiadiazolamines and related compounds, pharmaceutical compositions, methods of inhibiting Rho-associated protein kinase, and methods of treating inflammatory disorders, immune disorders, fibrotic disorders, and other medical disorders using such compounds. An exemplary indazolyl thiadiazolamine compound is an N-(3-(5-((1H-indazol-5-yl)amino)-1,2,4-thiadiazol-3-yl)phenyl)-heteroaryl-carboxamide compound.