The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 11, 2020

Filed:

Nov. 21, 2017
Applicants:

University of Miami, Miami, FL (US);

U.s.a., Represented BY the Department of Veterans Affairs, Washington, DC (US);

Inventors:

Andrew Schally, Miami Beach, FL (US);

Joshua M. Hare, Miami Beach, FL (US);

Norman Block, Hollywood, FL (US);

Samirah Gomes, Miami Beach, FL (US);

Rosemeire M. Kanashiro-Takeuchi, Miami, FL (US);

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/25 (2006.01); C07K 14/60 (2006.01); A61K 38/16 (2006.01);
U.S. Cl.
CPC ...
A61K 38/16 (2013.01);
Abstract

Disclosed herein are compositions of GHRH agonists and peptides, and methods to treat disorders, such as ischemia and reperfusion injury. In one embodiment, a method of treating a reperfusion injury in a subject in need may involve administering a therapeutically effective amount of at least one GHRH agonist peptide to the subject. In additional embodiment, a method of promoting vasculogenesis in a mammal may involve administering a therapeutically effective amount of at least one GHRH agonist peptide to the subject. In a further embodiment, a method of promoting differentiation of mesenchymal stem cells into endothelial cells may involve contacting mesenchymal stem cells with at least one GHRH agonist peptide.


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