The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2020
Filed:
Jul. 16, 2015
Applicant:
Transgene SA, Illkirch Graffenstaden, FR;
Inventors:
Nathalie Silvestre, Ergersheim, FR;
Michel Geist, Brumath, FR;
Karola Rittner, Strasbourg, FR;
Jean-Baptiste Marchand, Obernai, FR;
Christine Thioudellet, Strasbourg, FR;
Assignee:
Transgene S.A., Illkirch Graffenstaden, unknown;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/768 (2015.01); C07K 16/28 (2006.01); A61K 9/00 (2006.01); C07K 14/535 (2006.01); C12N 7/00 (2006.01); C12N 9/10 (2006.01); C12N 9/80 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/768 (2013.01); A61K 9/0019 (2013.01); C07K 14/535 (2013.01); C07K 16/2896 (2013.01); C12N 7/00 (2013.01); C12N 9/1077 (2013.01); C12N 9/80 (2013.01); C12Y 204/02009 (2013.01); C12Y 305/01023 (2013.01); A61K 2039/505 (2013.01); A61K 2039/5256 (2013.01); C07K 16/2818 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C07K 2317/55 (2013.01); C07K 2317/622 (2013.01); C12N 2710/24121 (2013.01); C12N 2710/24132 (2013.01);
Abstract
The present invention provides an oncolytic virus comprising nucleotide sequence(s) encoding one or more immune checkpoint modulator(s). It also concerns a pharmaceutical composition comprising effective amount of said oncolytic virus and, eventually, a pharmaceutically acceptable vehicle and its use for treating proliferative diseases such as cancers.