The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2020
Filed:
Aug. 25, 2017
Applicant:
Rhode Island Hospital, Providence, RI (US);
Inventors:
Qian Chen, Barrington, RI (US);
Yupeng Chen, Mansfield, MA (US);
Hongchuan Yu, Mansfield, MA (US);
Michael G. Ehrlich, Providence, RI (US);
Assignee:
Rhode Island Hospital, Providence, RI (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 31/519 (2006.01); C12Q 1/6881 (2018.01); A61K 49/00 (2006.01); C12Q 1/6883 (2018.01); C12Q 1/6886 (2018.01); A61K 47/69 (2017.01); G01N 33/68 (2006.01); A61K 9/51 (2006.01); A61K 9/08 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 9/0019 (2013.01); A61K 9/0092 (2013.01); A61K 9/08 (2013.01); A61K 9/5123 (2013.01); A61K 9/5146 (2013.01); A61K 47/6949 (2017.08); A61K 49/0095 (2013.01); C12Q 1/6881 (2013.01); C12Q 1/6883 (2013.01); C12Q 1/6886 (2013.01); G01N 33/6893 (2013.01); C12N 15/113 (2013.01); C12N 15/1137 (2013.01); C12N 15/1138 (2013.01); C12N 2310/14 (2013.01); C12N 2320/32 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/178 (2013.01); C12Y 304/24812 (2013.01); G01N 2800/102 (2013.01); Y02A 50/401 (2018.01);
Abstract
The compositions and methods of the invention provide compositions and methods for preferential targeting of tissues to delivery therapeutic or diagnostic agents. For example, such compounds are useful in the treatment of joint disorders those affecting articulating joints, e.g., injury-induced osteoarthritis as well as autoimmune diseases affecting joint tissue such as rheumatoid arthritis.