The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2020
Filed:
Apr. 30, 2014
Applicant:
The Methodist Hospital, Houston, TX (US);
Inventors:
David S. Baskin, Houston, TX (US);
Martyn Alun Sharpe, Houston, TX (US);
Assignee:
THE METHODIST HOSPITAL, Houston, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); A61K 31/435 (2006.01); A61K 31/4375 (2006.01); A61K 31/4745 (2006.01); A61K 45/06 (2006.01); A61K 47/48 (2006.01); A61N 5/10 (2006.01);
U.S. Cl.
CPC ...
A61K 31/44 (2013.01); A61K 31/435 (2013.01); A61K 31/4375 (2013.01); A61K 31/4745 (2013.01); A61K 45/06 (2013.01); A61K 47/48061 (2013.01); A61N 5/10 (2013.01);
Abstract
Disclosed are compound for targeting chemotherapeutic agents to mammalian mitochondria. Also disclosed are monoamine oxidase-specific compositions, and methods of using them for the selective therapy of mammalian cancers, and in particular, in the treatment of human gliomas. Also disclosed are methods employing the novel targeted chemotherapeutics with one or more conventional anti-cancer therapies, including, for example, radiotherapy, or multi-drug regimens.