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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10551390 B1

PDFFull Text
Date of Patent:
Feb. 04, 2020

Filed:

Jul. 18, 2015

Lysine monomethylated derivative and corresponding antibody and use thereof

Applicant:

Pmt Biolabs Inc, Hangzhou, CN;

Inventor:

Zhongyi Cheng, Hangzhou, CN;

Assignee:

PMT Biolabs Inc., Hangzhou, CN;

Attorney:

Lathrop Gage LLP

Primary Examiner:

Shafiqul Haq

Int. Cl.
CPC ...
C07K 7/08 (2006.01); C07K 16/44 (2006.01); G01N 33/68 (2006.01); C07C 233/47 (2006.01); G01N 33/53 (2006.01); C07K 16/18 (2006.01); C07K 14/435 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6848 (2013.01); C07C 233/47 (2013.01); C07K 7/08 (2013.01); C07K 14/43504 (2013.01); C07K 16/18 (2013.01); C07K 16/44 (2013.01); G01N 33/53 (2013.01); C07K 2317/34 (2013.01); C07K 2317/92 (2013.01); G01N 2440/12 (2013.01);
Abstract

Provided are artificially synthesized modified mono-methylated lysines and modified mono-methylated lysine derivatized polypeptides. Also provided is an antibody produced by using this modified mono-methylated lysine and modified monomethylated lysine derivatized polypeptide as an antigen, the antibody can be used in recognizing and enriching the modified polypeptide after the lysine mono-methylated polypeptide being derivatized in vitro. Also provided are a preparation method of said antibody, a method for identifying and quantifying the lysine mono-methylated modified substrate in cell or tissue by using proteomics approach of affinity enrichment for specific antibody and mass spectrometry.

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Cheng, Zhongyi. (2020). Lysine monomethylated derivative and corresponding antibody and use thereof (U.S. Patent No. 10551390). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10551390

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