The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2020
Filed:
May. 05, 2010
Xiaobo Wang, San Diego, CA (US);
Wei Ouyang, San Diego, CA (US);
Nan LI, San Diego, CA (US);
Biao Xi, San Diego, CA (US);
Yama A. Abassi, San Diego, CA (US);
Xiao Xu, San Diego, CA (US);
Xiaobo Wang, San Diego, CA (US);
Wei Ouyang, San Diego, CA (US);
Nan Li, San Diego, CA (US);
Biao Xi, San Diego, CA (US);
Yama A. Abassi, San Diego, CA (US);
Xiao Xu, San Diego, CA (US);
ACEA Biosciences, Inc., San Diego, CA (US);
Abstract
Devices and methods for performing extracellular recording of cells, such as excitable cells, cardiomyocytes, and cardiomyocyte precursor cells is provided. An exemplary device includes a nonconductive substrate forming or provided as a base of one or more wells; a recording electrode positioned on the substrate within the well, wherein the recording electrode is accessible to cells when a cell sample is added to the device; and a reference electrode positioned within the well in a cell-free zone, the cell-free zone characterized as free from contact with cells when the cell sample is added to the device, thereby preventing contact between cells and the reference electrode.