The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 04, 2020

Filed:

Jul. 31, 2017
Applicant:

Princeton University, Princeton, NJ (US);

Inventors:

Han Cao, San Diego, CA (US);

Jonas O. Tegenfeldt, Lund, SE;

Stephen Chou, Princeton, NJ (US);

Robert H. Austin, Princeton, NJ (US);

Assignee:

Princeton University, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); G01N 21/00 (2006.01); G01N 33/00 (2006.01); G01N 21/64 (2006.01); B81C 1/00 (2006.01); B82Y 30/00 (2011.01); G01N 33/487 (2006.01); G03F 7/20 (2006.01);
U.S. Cl.
CPC ...
G01N 21/6486 (2013.01); B01L 3/502707 (2013.01); B01L 3/502746 (2013.01); B01L 3/502761 (2013.01); B81C 1/00119 (2013.01); B82Y 30/00 (2013.01); G01N 33/48721 (2013.01); G03F 7/2008 (2013.01); B01L 3/502715 (2013.01); B01L 2200/027 (2013.01); B01L 2200/0663 (2013.01); B01L 2200/12 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/0896 (2013.01); B01L 2400/0415 (2013.01); B01L 2400/086 (2013.01); B81B 2201/058 (2013.01); B81C 2201/0157 (2013.01); B81C 2201/0159 (2013.01); Y10T 436/143333 (2015.01);
Abstract

A fluidic chip includes at least one nanochannel array, the nanochannel array including a surface having a nanofluidic area formed in the material of the surface; a microfluidic area on said surface; a gradient interface area having a gradual elevation of height linking the microfluidic area and the nanofluidic area; and a sample reservoir capable of receiving a fluid in fluid communication with the microfluidic area. In another embodiment, a fluidic chip includes at least one nanochannel array, the nanochannel array includes a surface having a nanofluidic area formed in the material of the surface; a microfluidic area on said surface; and a gradient interface area linking the microfluidic area and the nanofluidic area, where the gradient interface area comprises a plurality of gradient structures, and the lateral spacing distance between said gradient structures decreases towards said nanofluidic area; and a sample reservoir capable of receiving a fluid in fluid communication with the microfluidic area.


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