The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 04, 2020

Filed:

Jan. 26, 2015
Applicant:

Roy C. Levitt, Miami, FL (US);

Inventor:

Roy C. Levitt, Jr., Miami, FL (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/20 (2006.01); A61K 9/00 (2006.01); A61K 31/70 (2006.01); C12N 15/113 (2010.01); C07K 14/715 (2006.01); A61K 31/7088 (2006.01); A61K 31/713 (2006.01); A61K 38/17 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1136 (2013.01); A61K 9/007 (2013.01); A61K 9/008 (2013.01); A61K 9/0075 (2013.01); A61K 9/0078 (2013.01); A61K 31/70 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61K 38/1793 (2013.01); A61K 38/20 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); C07K 14/7155 (2013.01); C12N 15/113 (2013.01); C07K 2319/30 (2013.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01); C12N 2320/30 (2013.01);
Abstract

The present invention is drawn to methods and compositions for treating inflammatory disorders of the lower airways, comprising administering an effective amount of an agent, which modulates the expression and/or activity of a proinflammatory cytokine or fragment thereof, preferably in a human. The proinflammatory cytokine contemplated by the invention includes IL-1, IL-6, IL-8 and TNF-alpha. The present invention describes a kit comprising a delivery device and a pharmaceutical composition for administration of the agent. The pharmaceutical composition includes at least one proinflammatory cytokine inhibitor, optionally one or more additional active ingredients, and at least one pharmaceutically active carrier. The delivery device further comprises a nebulizer, an inhaler, a powder dispenser, an intrapulmonary aerosolizer and a sub-miniature aerosolizer.


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