The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2020
Filed:
Apr. 11, 2014
Applicant:
Ipsen Bioinnovation Limited, Abingdon, Oxon, GB;
Inventors:
Assignee:
IPSEN BIOINNOVATION LIMITED, Abingdon, Oxfordshire, GB;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/33 (2006.01); C12N 9/50 (2006.01); C12N 9/64 (2006.01); C07K 7/08 (2006.01); C07K 14/48 (2006.01); C07K 14/575 (2006.01); C07K 14/60 (2006.01); C07K 14/65 (2006.01); C07K 14/82 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/50 (2013.01); C07K 7/086 (2013.01); C07K 14/33 (2013.01); C07K 14/48 (2013.01); C07K 14/575 (2013.01); C07K 14/5759 (2013.01); C07K 14/57563 (2013.01); C07K 14/60 (2013.01); C07K 14/65 (2013.01); C07K 14/82 (2013.01); C12N 9/6489 (2013.01); A61K 38/00 (2013.01); C07K 2319/035 (2013.01); C07K 2319/06 (2013.01); C07K 2319/33 (2013.01); C07K 2319/50 (2013.01);
Abstract
The present invention relates to a method for suppressing or treating cancer, in particular to a method for suppressing or treating one or more of colorectal cancer, breast cancer, prostate cancer and/or lung cancer. The therapy employs use of a non-cytotoxic protease, which is targeted to a growth hormone-secreting cell such as to a pituitary cell. When so delivered, the protease is internalised and inhibits secretion/transmission of growth hormone from said cell. The present invention also relates to polypeptides and nucleic acids for use in said methods.