The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2020
Filed:
Dec. 09, 2016
Kyowa Hakko Kirin Co., Ltd, Tokyo, JP;
Kyushu University, National University Corporation, Fukuoka-shi, Fukuoka, JP;
Shin-ichiro Takayanagi, Tokyo, JP;
Hitomi Tomura, Takasaki, JP;
Tomonori Tawara, Tokyo, JP;
Yoshimasa Inagaki, Tokyo, JP;
Tsuguo Kubota, Tokyo, JP;
Koichi Akashi, Fukuoka, JP;
Yoshikane Kikushige, Fukuoka, JP;
KYOWA KIRIN CO., LTD, Tokyo, JP;
Kyushu University, National University Corporation, Fukuoka-shi, Fukuoka, JP;
Abstract
Disclosed are an anti-human TIM-3 antibody having high ADCC activity or antibody fragment thereof by screening a monoclonal antibody or antibody fragment thereof which binds to the amino acid sequence of the extracellular region of TIM-3 or its three-dimensional structure and exhibits ADCC activity; a hybridoma which produces the antibody; a DNA encoding the antibody; a vector comprising the DNA; a transformant which is obtainable by introducing the vector; a method for producing the antibody or the antibody fragment thereof which comprises using the hybridoma or the transformant; and a therapeutic agent and a diagnostic agent comprising the antibody or the antibody fragment thereof as an active ingredient.