The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 04, 2020

Filed:

Apr. 23, 2018
Applicant:

Hanmi Pharm. Co., Ltd., Hwaseong-si, Gyeonggi-do, KR;

Inventors:

Jin Sun Kim, Yongin-si, KR;

Dae Jin Kim, Hwaseong-si, KR;

Sang Hyun Lee, Seoul, KR;

Sung Youb Jung, Suwon-si, KR;

Se Chang Kwon, Seoul, KR;

Assignee:

Hanmi Pharm. Co., Ltd., Hwaseong-si, Gyeonggi-do, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/22 (2006.01); A61K 38/26 (2006.01); C07K 14/575 (2006.01); C07K 14/605 (2006.01); C07K 16/00 (2006.01); C07K 16/30 (2006.01); A61K 47/64 (2017.01);
U.S. Cl.
CPC ...
C07K 14/575 (2013.01); A61K 38/22 (2013.01); A61K 47/643 (2017.08); A61K 47/6435 (2017.08); C07K 14/605 (2013.01); C07K 16/00 (2013.01); C07K 16/3046 (2013.01); C07K 2319/30 (2013.01); C07K 2319/31 (2013.01);
Abstract

Disclosed are a composition for preventing or treating diabetes, disbesity or diabetic complications, containing an oxyntomodulin analog as an active ingredient and a method for treating diabetes, diabesity or diabetic complications, including administering a pharmaceutically effective amount of an oxyntomodulin analog to a subject. The oxyntomodulin analog shows a greater activity to activate a GLP-1 receptor and a glucagon receptor, than native oxyntomodulin. The oxyntomodulin analog induces an expansion of beta-cells and increases insulin secretion, thereby reducing blood glucose levels that were increased due to a high-calorie and high-fat diet. The oxyntomodulin analog induces decreases in a body weight and appetite to improve insulin sensitivity and is useful in maintaining normal blood glucose levels.


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