The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 04, 2020

Filed:

Aug. 07, 2013
Applicant:

Daiichi Sankyo Company, Limited, Chuo-ku, Tokyo, JP;

Inventors:

Daisuke Nishimiya, Sumida-ku, JP;

Ryuji Hashimoto, Yachiyo, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01); C12N 15/10 (2006.01); C40B 50/00 (2006.01); C07K 14/81 (2006.01); C12Q 1/37 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); C12N 15/1037 (2013.01); C07K 14/81 (2013.01); C07K 14/811 (2013.01); C12N 15/1044 (2013.01); C12N 2510/00 (2013.01); C12Q 1/37 (2013.01); C40B 50/00 (2013.01); G01N 2500/00 (2013.01);
Abstract

Disclosed are compositions and method related to variants of SPINK2 that bind to targets other than an endogenous target of SPINK2. In one embodiment, a peptide is provided that comprises the amino acid sequence SEQ ID NO: 1. In further embodiments, an amino acid sequences encoded by nucleotide positions 4 to 42 and/or nucleotide positions 94 to 189 in the nucleotide sequence of SEQ ID NO: 14 flank the amino terminus and the carboxyl terminus, respectively, of the amino acid sequence. In another embodiment, a peptide is provided that comprises an amino acid sequence derived from the amino acid sequence of SEQ ID NO: 1 in which a conservative substitution, deletion, addition and/or insertion of 1 to 5 (inclusive) amino acids has occurred at amino acids other than the 1st Xaa to the 12th Xaa counting from the amino terminus.


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