The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2020
Filed:
Oct. 19, 2016
Applicant:
Bristol-myers Squibb Company, Princeton, NJ (US);
Inventors:
Ashok Vinayak Purandare, Pennington, NJ (US);
Kurt Zimmermann, Durham, CT (US);
Honghe Wan, Pennington, NJ (US);
Assignee:
Bristol-Myers Squibb Company, Princeton, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/53 (2006.01); C07D 487/04 (2006.01); A61P 19/02 (2006.01); A61P 17/06 (2006.01); A61P 35/02 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61P 17/06 (2018.01); A61P 19/02 (2018.01); A61P 35/02 (2018.01);
Abstract
The invention provides pharmaceutically active compounds of formula (I) and prodrugs thereof. The formula (I) 2-(aminophenylamino)-4-amino-7-cyano-imidazo[2,1-f][1,2,4]triazine derivatives inhibit CK2 protein kinase activity, thereby making them useful for treating cancer, psoriasis and rheumatoid arthritis.