The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2020
Filed:
Aug. 15, 2016
Applicant:
San Diego State University Research Foundation, San Diego, CA (US);
Inventors:
Jeffrey L. Gustafson, San Diego, CA (US);
Davis E. Smith, San Diego, CA (US);
David Hecht, San Diego, CA (US);
Isaac Marquez, San Diego, CA (US);
Sean Toenjes, San Diego, CA (US);
Assignee:
San Diego State University Foundation, San Diego, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 473/34 (2006.01); C07D 487/04 (2006.01); A61P 35/02 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61P 35/02 (2018.01);
Abstract
The invention provides a series of conformationally stable kinase inhibitors, and methods of using the kinase inhibitors. The effect of atropisomerism on kinase selectivity was assessed, finding improved selectivity compared to rapidly interconverting parent compounds.