The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2020
Filed:
Dec. 14, 2018
Applicant:
Genentech, Inc., South San Francisco, CA (US);
Inventors:
James John Crawford, San Francisco, CA (US);
Aleksandr Kolesnikov, San Francisco, CA (US);
Jianwen A. Feng, San Mateo, CA (US);
Assignee:
Genentech, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 417/10 (2006.01); A61P 27/14 (2006.01); A61P 37/06 (2006.01); A61P 17/00 (2006.01); A61P 19/02 (2006.01); A61P 1/00 (2006.01); A61P 11/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 417/10 (2013.01); A61P 1/00 (2018.01); A61P 11/00 (2018.01); A61P 17/00 (2018.01); A61P 19/02 (2018.01); A61P 27/14 (2018.01); A61P 37/06 (2018.01);
Abstract
The invention relates to compounds of formula (I): wherein Q, A, A, A, A, A, A, A, R, Rand Rare as described herein. Compounds of formula (I) and pharmaceutical compositions thereof are useful in the treatment of diseases and disorders in which undesired or over-activation of NF-kB signaling is observed.