The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 04, 2020

Filed:

Mar. 04, 2014
Applicant:

Stc.unm, Albuquerque, NM (US);

Inventors:

Erin Damita Milligan, Placitas, NM (US);

Jeffrey P. Norenberg, Albuquerque, NM (US);

Assignee:

STC.UNM, Albuquerque, NM (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4166 (2006.01); A61K 51/04 (2006.01); A61K 31/4174 (2006.01); A61K 38/18 (2006.01); A61K 38/20 (2006.01); A61K 38/34 (2006.01);
U.S. Cl.
CPC ...
A61K 51/0453 (2013.01); A61K 31/4174 (2013.01); A61K 38/1841 (2013.01); A61K 38/2013 (2013.01); A61K 38/2026 (2013.01); A61K 38/2066 (2013.01); A61K 38/2086 (2013.01); A61K 38/34 (2013.01);
Abstract

In one embodiment, the invention provides a method of treating a subject suffering from chronic neuropathic pain and/or allodynia by administering a therapeutically-effective amount of at least one LFA1 antagonist to the subject. In a preferred embodiment, the invention provides a method of treating a subject suffering from chronic neuropathic pain and/or allodynia, the method comprising administering intrathecally to the subject a therapeutically-effective amount of microparticles comprising PLGA-encapsulated pDNA-IL-10, optionally in combination with a therapeutically-effective amount of intrathecally-administered CpG oligodeoxynucleotide (CpG ODN) and/or at least one LFA1 antagonist.


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