The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2020
Filed:
Apr. 07, 2016
Memorial Sloan Kettering Cancer Center, New York, NY (US);
Cornell University, Ithaca, NY (US);
The Curators of the University of Missouri, Columbia, MO (US);
Michelle S. Bradbury, New York, NY (US);
Thomas P. Quinn, Columbia, MO (US);
Feng Chen, New York, NY (US);
Barney Yoo, New York, NY (US);
Jason Lewis, New York, NY (US);
Ulrich Wiesner, Ithaca, NY (US);
Kai Ma, Ithaca, NY (US);
Memorial Sloan Kettering Cancer Center, New York, NY (US);
Cornell University, Ithaca, NY (US);
The Curators of the University of Missouri, Columbia, MO (US);
Abstract
Disclosed herein are nanoparticle immunoconjugates useful for therapeutics and/or diagnostics. The immunoconjugates have diameter (e.g., average diameter) no greater than 20 nanometers (e.g., as measured by dynamic light scattering (DLS) in aqueous solution, e.g., saline solution). In certain embodiments, the conjugates are silica-based nanoparticles with single chain antibody fragments attached thereto.