The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2020
Filed:
Jul. 29, 2016
The U.s.a., As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);
The Children's Hospital of Philadelphia, Philadelphia, PA (US);
Dimiter S. Dimitrov, Frederick, MD (US);
Yang Feng, Frederick, MD (US);
John M. Maris, Philadelphia, PA (US);
Zhongyu Zhu, Frederick, MD (US);
Robyn Tovah Sussman, Philadelphia, PA (US);
The United States of America, as represented by the Secretary, Department of Health and Human Services, Bethesda, MD (US);
The Children's Hospital of Philadelphia, Philadelphia, PA (US);
Abstract
The identification and characterization of two fully human CD56-specific monoclonal antibodies targeting spatially separated epitopes proximal and distal to the plasma membrane is described. Also described are antibody-drug conjugates (ADCs) of the identified antibodies and their use for targeting CD56-expressing tumor cells.