The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 04, 2020

Filed:

Aug. 24, 2016
Applicants:

Xiamen University, Xiamen, CN;

Yang Sheng Tang Company, Ltd., Haikou, CN;

Inventors:

Tianying Zhang, Xiamen, CN;

Quan Yuan, Xiamen, CN;

Xueran Guo, Xiamen, CN;

Ying Zhang, Xiamen, CN;

Qinjian Zhao, Xiamen, CN;

Jun Zhang, Xiamen, CN;

Ningshao Xia, Xiamen, CN;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C07K 14/005 (2006.01); C12Q 1/70 (2006.01); G01N 33/569 (2006.01); A61K 31/7088 (2006.01); A61K 39/29 (2006.01); A61K 39/385 (2006.01); C12N 15/62 (2006.01); C07K 19/00 (2006.01); C12N 7/04 (2006.01); A61P 31/20 (2006.01); A61P 35/00 (2006.01); A61K 39/39 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/292 (2013.01); A61K 39/29 (2013.01); A61K 39/385 (2013.01); A61K 39/39 (2013.01); A61P 31/20 (2018.01); A61P 35/00 (2018.01); C07K 19/00 (2013.01); C12N 7/00 (2013.01); C12N 7/04 (2013.01); C12N 15/62 (2013.01); C12N 2730/10122 (2013.01); C12N 2730/10123 (2013.01);
Abstract

The invention relates to a polypeptide carrier for presenting a target polypeptide, and use thereof. In particular, the invention relates to a nucleic acid molecule, comprising a nucleotide sequence encoding a polypeptide carrier, and being used for insertion of a nucleotide sequence encoding a target polypeptide. In addition, the invention further relates to a recombinant protein comprising the polypeptide carrier and a target polypeptide. Furthermore, the invention further relates to use of the nucleic acid molecule and the recombinant protein. In addition, the invention further relates to a vaccine or a pharmaceutical composition useful for preventing, alleviating or treating HBV infection or a disease associated with HBV infection (e.g., hepatitis B), comprising a recombinant protein comprising the polypeptide carrier of the invention and an epitope from HBV.


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