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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10548972 B1

PDFFull Text
Date of Patent:
Feb. 04, 2020

Filed:

Jan. 06, 2015

Gene-deleted variant strain of porcine pseudorabies virus, vaccine composition, method of making the same and use thereof

Applicant:

Pulike Biological Engineering, Inc., Luoyang, CN;

Inventors:

Kegong Tian, Luoyang, CN;

Xuke Zhang, Luoyang, CN;

Jinzhong Sun, Luoyang, CN;

Feifei Tan, Luoyang, CN;

Assignee:

PULIKE BIOLOGICAL ENGINEERING, INC., , CN;

Attorney:

Fish IP Law, LLP

Primary Examiner:

M Franco G Salvoza

Int. Cl.
CPC ...
C12N 7/00 (2006.01); A61K 39/00 (2006.01); A61K 39/245 (2006.01); C12N 7/04 (2006.01); A61K 39/12 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 39/245 (2013.01); A61K 39/12 (2013.01); A61K 45/06 (2013.01); C12N 7/00 (2013.01); C12N 7/04 (2013.01); A61K 2039/5252 (2013.01); A61K 2039/5254 (2013.01); A61K 2039/543 (2013.01); A61K 2039/545 (2013.01); A61K 2039/552 (2013.01); C12N 2710/16011 (2013.01); C12N 2710/16634 (2013.01); C12N 2710/16721 (2013.01); C12N 2710/16734 (2013.01); C12N 2710/16762 (2013.01); C12N 2710/16771 (2013.01); C12N 2770/20071 (2013.01);
Abstract

The present invention provides an attenuated strain of porcine pseudorabies virus (PRV), in which said attenuated strain of PRV is a variant strain of PRV with inactivation of gI/gE/11K/28K proteins. In addition, the present invention also provides a vaccine composition comprising the attenuated strain of PRV as an antigen, a preparation method and use thereof. Proved by immunogenicity and pathogenicity testing of the live vaccine, said live PRV vaccine can provide a good protection for pigs with no clinical signs observed, indicating excellent immune protection.

Find Patent Forward Citations

Tian, Kegong. (2020). Gene-deleted variant strain of porcine pseudorabies virus, vaccine composition, method of making the same and use thereof (U.S. Patent No. 10548972). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10548972

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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