The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 04, 2020

Filed:

Jan. 23, 2018
Applicant:

Metro International Biotech, Llc, Birmingham, MI (US);

Inventors:

Karl D. Normington, Prides Crossing, MA (US);

David A. Sinclair, Chestnut Hill, MA (US);

David J. Livingston, Barrington, RI (US);

James M. McKearin, Litchfield, NH (US);

Bruce Szczepankiewicz, Hopkinton, MA (US);

Jonathan N. Kremsky, Arlington, MA (US);

Assignee:

Metro International Biotech, LLC, Birmingham, MI (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/04 (2006.01); A61K 31/70 (2006.01); A61K 31/706 (2006.01); A61K 31/443 (2006.01); A61K 31/661 (2006.01); C07H 19/048 (2006.01); C07F 9/06 (2006.01); C07F 9/547 (2006.01); C07H 11/04 (2006.01); C07H 19/04 (2006.01); A61K 31/7052 (2006.01);
U.S. Cl.
CPC ...
A61K 31/706 (2013.01); A61K 31/443 (2013.01); A61K 31/661 (2013.01); C07F 9/06 (2013.01); C07F 9/547 (2013.01); C07H 11/04 (2013.01); C07H 19/048 (2013.01); A61K 31/7052 (2013.01); C07H 19/04 (2013.01);
Abstract

The invention relates to compositions of nicotinamide mononucleotide derivatives and their methods of use. The invention also relates to methods of preparing nicotinamide mononucleotide derivatives. The invention relates to pharmaceutical compositions and nutritional supplements containing a nicotinamide mononucleotide derivative. The invention relates to methods of using nicotinamide mononucleotide derivatives that promote the increase of intracellular levels of nicotinamide adenine dinucleotide (NAD+) in cells and tissues for treating diseases and improving cell and tissue survival.


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