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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10548877 B1

PDFFull Text
Date of Patent:
Feb. 04, 2020

Filed:

Mar. 09, 2017

Aromatic ring compound

Applicant:

Takeda Pharmaceutical Company Limited, Osaka-shi, Osaka, JP;

Inventors:

Masaki Ogino, Kanagawa, JP;

Eiji Kimura, Kanagawa, JP;

Shinkichi Suzuki, Kanagawa, JP;

Kouji Fuji, Kanagawa, JP;

Tomohiro Ohashi, Kanagawa, JP;

Makoto Fushimi, Kanagawa, JP;

Kei Masuda, Kanagawa, JP;

Tatsuki Koike, Kanagawa, JP;

Takeshi Wakabayashi, Kanagawa, JP;

Jinichi Yonemori, Kanagawa, JP;

Masami Yamada, Kanagawa, JP;

Assignee:

Takeda Pharmaceutical Company Limited, Osaka, JP;

Attorney:

Hamre, Schumann, Mueller & Larson, P.C.

Primary Examiner:

Timothy R Rozof

Int. Cl.
CPC ...
A61K 31/4192 (2006.01); A61K 31/415 (2006.01); A61K 31/4155 (2006.01); A61K 31/427 (2006.01); A61K 31/4406 (2006.01); A61K 31/4439 (2006.01); A61P 25/20 (2006.01); A61P 25/28 (2006.01); A61P 25/18 (2006.01); A61P 25/16 (2006.01); C07D 213/56 (2006.01); C07D 231/12 (2006.01); C07D 249/06 (2006.01); C07D 401/04 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4192 (2013.01); A61K 31/415 (2013.01); A61K 31/4155 (2013.01); A61K 31/427 (2013.01); A61K 31/4406 (2013.01); A61K 31/4439 (2013.01); A61P 25/16 (2018.01); A61P 25/18 (2018.01); A61P 25/20 (2018.01); A61P 25/28 (2018.01); C07D 213/56 (2013.01); C07D 231/12 (2013.01); C07D 249/06 (2013.01); C07D 401/04 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01);
Abstract

Provided is a compound having a cholinergic muscarine M1 receptor positive allosteric modulator activity. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof has a cholinergic muscarine M1 receptor positive allosteric modulator activity, and is useful as a prophylactic or therapeutic drug for Alzheimer's disease, schizophrenia, pain, sleep disorder, Parkinson's disease dementia, dementia with Lewy bodies and the like.

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