The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2020
Filed:
Nov. 28, 2017
Applicant:
Hubei Soundny Biotechnology Co., Ltd., Wuhan, CN;
Inventor:
Bo Huang, Wuhan, CN;
Assignee:
HUBEI SOUNDNY BIOTECHNOLOGY CO., LTD., Hubei, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/02 (2006.01); A61K 35/76 (2015.01); A61K 9/50 (2006.01); C12N 7/00 (2006.01); A61K 35/13 (2015.01); A61K 35/761 (2015.01);
U.S. Cl.
CPC ...
A61K 9/5068 (2013.01); A61K 35/13 (2013.01); A61K 35/76 (2013.01); A61K 35/761 (2013.01); C12N 7/00 (2013.01); C12N 7/02 (2013.01); C12N 2720/12032 (2013.01); C12N 2760/20232 (2013.01); C12N 2760/20251 (2013.01);
Abstract
The present invention provides an oncolytic virus formulation and preparation method thereof. The oncolytic virus formulation comprises cell vesicles derived from apoptotic tumor cells and oncolytic viruses coated in the cell vesicles as an effective component. The oncolytic virus formulation uses cell vesicles derived from tumor cells themselves to coat the oncolytic viruses, so as to evade the body's immune system attack and can be targeted to the tumor treatment site, and improve the tumor-killing effect.