The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 04, 2020

Filed:

Dec. 08, 2016
Applicant:

Massachusetts Institute of Technology, Cambridge, MA (US);

Inventors:

Aaron C. Anselmo, Cambridge, MA (US);

Robert S. Langer, Newton, MA (US);

Ana Jaklenec, Lexington, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/16 (2006.01); A61K 35/741 (2015.01); A61K 35/742 (2015.01); A61K 35/745 (2015.01); A61K 35/747 (2015.01);
U.S. Cl.
CPC ...
A61K 9/1652 (2013.01); A61K 9/1641 (2013.01); A61K 35/741 (2013.01); A61K 35/742 (2013.01); A61K 35/745 (2013.01); A61K 35/747 (2013.01);
Abstract

Methods of encapsulating microorganisms, or components thereof, for targeted enteric delivery to an animal host have been developed. In particular, the encapsulation provides a prolonged survival, extended retention and a pH-sensitive release of the encapsulated microorganisms or antigenic components thereof at targeted sites within the gastrointestinal tract. The formulations are useful for diagnostic, therapeutic and prophylactic purposes and can alter a host's microbial composition associated with a condition or a disease state.


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