The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2020
Filed:
Jan. 09, 2015
Applicant:
Attagene, Inc., Research Triangle Park, NC (US);
Inventors:
Sergei S. Makarov, Morrisville, NC (US);
Ming Zheng, Chapel Hill, NC (US);
Assignee:
ATTAGENE, INC., Research Triangle Park, NC (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6897 (2018.01); C12Q 1/6886 (2018.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6897 (2013.01); C12Q 1/6886 (2013.01); G01N 33/5014 (2013.01); G01N 2500/10 (2013.01);
Abstract
A protein reporter system comprising at least one reporter including a response element responsive to the binding of a transcription factor, a secreted enzyme backbone and a recognition region for specific binding of an antibody. Multiplexed assays for binding, assaying and quantifying the activity of transcription factors are also described, in which the assays use protein reporters in sets, libraries or other groupings, as necessary to achieve desired quantification.