The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2020
Filed:
Jun. 09, 2017
Applicant:
Pacific Biosciences of California, Inc., Menlo Park, CA (US);
Inventors:
Erik Miller, Berkeley, CA (US);
Keith Bjornson, Fremont, CA (US);
Kristofor Nyquist, Oakland, CA (US);
Satwik Kamtekar, Mountain View, CA (US);
Assignee:
Pacific Biosciences of California, Inc., Menlo Park, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6874 (2018.01); C12N 9/96 (2006.01); C12N 9/12 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6874 (2013.01); C12N 9/1241 (2013.01); C12N 9/96 (2013.01);
Abstract
The present invention provides methods, compositions, and systems for enriching compositions for polymerase enzyme complexes. In particular, the methods, compositions, and systems of the present invention remove free polymerases from the compositions using one or more purification steps, including protease treatment, thus enriching the compositions for polymerases complexed with a template nucleic acid.