The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2020
Filed:
Jan. 06, 2017
Pacific Biosciences of California, Inc., Menlo Park, CA (US);
Gene Shen, Santa Clara, CA (US);
Natasha Popovich, Belmont, CA (US);
Erik Miller, San Francisco, CA (US);
Satwik Kamtekar, Mountain View, CA (US);
Keith Bjornson, Fremont, CA (US);
Jeremiah Hanes, Woodside, CA (US);
Stephen Yue, Eugene, OR (US);
Lubomir Sebo, Hayward, CA (US);
Zhong Wang, Cupertino, CA (US);
Pacific Biosciences of California, Inc., Menlo Park, CA (US);
Abstract
Multi-biotinylated reactants are provided which can be used in divalent complexes for various applications such as colocalization, labeling, immobilization, and purification. Methods for constructing, purifying, and using the bis-biotinylated reactants are also provided. In certain embodiments, two bis-biotinylated reactants are bound to a single streptavidin tetramer to provide a complex having a 1:1 stoichiometry with respect to the bis-biotinylated reactants.