The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2020
Filed:
Dec. 06, 2017
Applicant:
Roche Molecular Systems, Inc., Pleasanton, CA (US);
Inventors:
Keith Bauer, San Rafael, CA (US);
Fred Reichert, San Leandro, CA (US);
Thomas W. Myers, Dublin, CA (US);
Assignee:
Roche Molecular Systems, Inc., Pleasanton, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/12 (2006.01); C12P 19/34 (2006.01); C12Q 1/6806 (2018.01);
U.S. Cl.
CPC ...
C12N 9/1252 (2013.01); C12P 19/34 (2013.01); C12Q 1/6806 (2013.01); C12Y 207/07007 (2013.01); Y02P 20/52 (2015.11);
Abstract
Disclosed are mutant DNA polymerases having increased 3'-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.