The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2020
Filed:
Mar. 12, 2015
Applicants:
Neurimmune Holding Ag, Schlieren, CH;
University of Zurich, Zurich, CH;
Inventors:
Jan Grimm, Dübendorf, CH;
Fabrice Heitz, Bartenheim, FR;
Fabian Wirth, St. Gallen, CH;
Tobias Welt, Zurich, CH;
Assignees:
Neurimmune Holding AG, Schlieren, CH;
University of Zurich, Zurich, CH;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); A61K 45/06 (2006.01); C07K 16/26 (2006.01); A01K 67/027 (2006.01); A61K 47/68 (2017.01); A61P 3/10 (2006.01); A61K 39/395 (2006.01); A61K 49/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/26 (2013.01); A01K 67/0275 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); A61K 47/6847 (2017.08); A61K 49/0008 (2013.01); A61P 3/10 (2018.01); A01K 2217/052 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0362 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01);
Abstract
Described are molecules specifically binding to human islet amyloid polypeptide (hIAPP) also known as amylin, particularly human-derived antibodies as well as fragments, derivatives and variants thereof for antagonizing islet amyloid polypeptide (IAPP) induced β-cell damage and impaired glucose tolerance which are symptoms typically associated with diabetes mellitus type 2 (T2D).