The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2020
Filed:
Oct. 23, 2015
Teva Pharmaceuticals Australia Pty Ltd, Macquarie Park, NSW, AU;
Collette Behrens, Macquarie Park, AU;
Anthony Doyle, Macquarie Park, AU;
Adam Clarke, Macquarie Park, AU;
Matthew Pollard, Macquarie Park, AU;
Teresa Domagala, Macquarie Park, AU;
Teva Pharmaceuticals Australia Pty Ltd, Macquarie Park, AU;
Abstract
The present invention provides a fusion polypeptide comprising a first domain and a second domain, wherein the first domain comprises a polypeptide ligand which binds to a cell surface-associated antigen and the second domain comprises aglycosylated interferon α 2b (IFNα2b) having a sequence of SEQ ID NO: 1 or SEQ ID NO: 2. The aglycosylated IFNα2b further comprises one or more amino acid substitutions or deletions which attenuate the activity of the aglycosylated IFNα2b.