The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 28, 2020

Filed:

Mar. 24, 2017
Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

Abdelghani Abe Achab, Melrose, MA (US);

Matthew P. Christopher, Brookline, MA (US);

Francesc Xavier Fradera Llinas, Brookline, MA (US);

Jason D. Katz, Newton Heights, MA (US);

Joey L. Methot, Westwood, MA (US);

Hua Zhou, Acton, MA (US);

Shimin Xu, Beijing, CN;

Jianmin Fu, Beijing, CN;

Ning Fu, Beijing, CN;

Yabin Li, Beijing, CN;

Xichao Wang, Beijing, CN;

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/00 (2006.01); C07D 473/00 (2006.01); A61P 37/02 (2006.01); A61P 11/06 (2006.01); A61P 19/02 (2006.01); A61P 35/00 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 473/00 (2013.01); A61P 11/06 (2018.01); A61P 19/02 (2018.01); A61P 35/00 (2018.01); A61P 37/02 (2018.01); C07D 519/00 (2013.01);
Abstract

The instant invention provides compounds of formula (I) which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflammation, asthma, COPD and cancer.


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