The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2020
Filed:
Apr. 23, 2018
Applicant:
The Scripps Research Institute, La Jolla, CA (US);
Inventors:
Edward Roberts, Fallbrook, CA (US);
Hugh Rosen, La Jolla, CA (US);
Steven Brown, San Diego, CA (US);
Miguel A. Guerrero, San Diego, CA (US);
Xuemei Peng, La Jolla, CA (US);
Ramulu Poddutoori, La Jolla, CA (US);
Assignee:
The Scripps Research Institute, La Jolla, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/04 (2006.01); C07D 413/14 (2006.01); C07D 271/06 (2006.01); C07D 471/04 (2006.01); A61K 31/4245 (2006.01); C07D 401/04 (2006.01); C07D 263/32 (2006.01);
U.S. Cl.
CPC ...
C07D 413/04 (2013.01); A61K 31/4245 (2013.01); C07D 271/06 (2013.01); C07D 413/14 (2013.01); C07D 471/04 (2013.01); C07D 263/32 (2013.01); C07D 401/04 (2013.01);
Abstract
Compounds that activate a sphingosine-1-phosphate receptor of the subtype 1 are provided. Certain compounds selectively activate the receptor subtype 1 in relation to the sphinogosine-1-phosphate receptor subtype 3. Uses and methods of inventive compounds for treatment of malconditions wherein activation, agonism, inhibition or antagonism of the S1P1 is medically indicated are provided.