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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10544113 B1

PDFFull Text
Date of Patent:
Jan. 28, 2020

Filed:

Mar. 03, 2017

Thiazolidinone compounds and use thereof

Applicant:

National Health Research Institutes, Miaoli County, TW;

Inventors:

Shau-Hua Ueng, Miaoli County, TW;

Shiu-Hwa Yeh, Miaoli County, TW;

Shu-Yu Lin, Miaoli County, TW;

Chuan Shih, Carmel, IN (US);

Horace Loh, Little Canada, MN (US);

Assignees:

National Health Research Institute, Miaoli County, TW;

Regents of the University of Minnesota, Minneapolis, MN (US);

Attorney:

Cesari & McKenna, LLP

Primary Examiner:

Laura L Stockton

Int. Cl.
CPC ...
C07D 277/14 (2006.01); A61K 31/426 (2006.01); C07D 417/10 (2006.01); A61K 31/427 (2006.01); C07D 417/12 (2006.01); A61K 31/4439 (2006.01); A61K 31/454 (2006.01); A61K 31/5377 (2006.01); C07H 17/02 (2006.01); C07D 417/04 (2006.01); C07D 277/54 (2006.01); C07D 249/08 (2006.01); A61K 31/433 (2006.01); C07D 417/14 (2006.01); A61K 31/497 (2006.01); A61K 31/506 (2006.01); A61K 31/402 (2006.01); C07D 207/27 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 277/14 (2013.01); A61K 31/402 (2013.01); A61K 31/426 (2013.01); A61K 31/427 (2013.01); A61K 31/433 (2013.01); A61K 31/4439 (2013.01); A61K 31/454 (2013.01); A61K 31/497 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); C07D 207/27 (2013.01); C07D 249/08 (2013.01); C07D 277/54 (2013.01); C07D 417/04 (2013.01); C07D 417/10 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07H 17/02 (2013.01);
Abstract

A pharmaceutical composition containing a compound of Formula (I) for treating an opioid receptor-associated condition. Also disclosed is a method for treating an opioid receptor-associated condition using such a compound. Further disclosed are two sets of thiazolidinone compounds of formula (I): (i) compounds each having an enantiomeric excess greater than 90% and (ii) compounds each being substituted with deuterium.

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