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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10544111 B1

PDFFull Text
Date of Patent:
Jan. 28, 2020

Filed:

Dec. 21, 2018

Heterocyclic compound

Applicant:

Takeda Pharmaceutical Company Limited, Osaka, JP;

Inventors:

Yoshihiro Banno, Kanagawa, JP;

Masahiro Kamaura, Kanagawa, JP;

Kazuaki Takami, Kanagawa, JP;

Koichiro Fukuda, Kanagawa, JP;

Shigekazu Sasaki, Kanagawa, JP;

Assignee:

TAKEDA PHARMACEUTICAL COMPANY LIMITED, Osaka, JP;

Attorney:

Haug Partners LLP

Primary Examiner:

Zinna Northington Davis

Int. Cl.
CPC ...
C07D 263/46 (2006.01); A61K 31/415 (2006.01); A61K 31/421 (2006.01); A61K 31/4418 (2006.01); A61K 31/505 (2006.01); C07D 231/12 (2006.01); C07D 231/22 (2006.01); C07D 239/34 (2006.01); C07D 263/38 (2006.01); C07D 213/65 (2006.01); A61P 27/02 (2006.01); C07D 213/70 (2006.01); C07K 14/47 (2006.01); C12N 15/09 (2006.01);
U.S. Cl.
CPC ...
C07D 263/46 (2013.01); A61K 31/415 (2013.01); A61K 31/421 (2013.01); A61K 31/4418 (2013.01); A61K 31/505 (2013.01); A61P 27/02 (2018.01); C07D 213/65 (2013.01); C07D 213/70 (2013.01); C07D 231/12 (2013.01); C07D 231/22 (2013.01); C07D 239/34 (2013.01); C07D 263/38 (2013.01); C07K 14/47 (2013.01); C12N 15/09 (2013.01);
Abstract

Provided is a heterocyclic compound having a superior RBP4-lowering action and useful as a medicament for the prophylaxis or treatment of a disease or symptom mediated by an increase in RBP4 or retinol supplied by RBP4. A compound represented by the formula (I): wherein each symbol is as defined in the Description, or a salt thereof has a superior RBP4-lowering action, and is useful as a medicament for the prophylaxis or treatment of a disease or symptom mediated by an increase in RBP4 or retinol supplied by RBP4.

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