The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2020
Filed:
Aug. 25, 2017
University of Washington Through Its Center for Commercialization, Seattle, WA (US);
Wesley C. Van Voorhis, Seattle, WA (US);
Wilhelmus G. J. Hol, Kenmore, WA (US);
Eric T. Larson, Shoreline, WA (US);
Dustin James Maly, Seattle, WA (US);
Ethan Merritt, Seattle, WA (US);
Kayode K. Ojo, Federal Way, WA (US);
UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR CO, Seattle, WA (US);
Abstract
Compositions and methods for the treatment of toxoplasmosis, caused by the infectious eukaryotic parasite() and for the treatment of cryptosporidiosis, caused by the infectious eukaryotic parasites() and() are described. In particular, the present disclosure is directed to compositions and methods for inhibiting eithercalcium dependent protein kinases (TgCDPKs) orandcalcium dependent protein kinases (CpCDPKs) using pyrazolopyrimidine and/or imidazo[1,5-a]pyrazine inhibitors, of the formula, wherein the variables X, Y, Z, L, R, and Rare defined herein.