The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2020
Filed:
Jun. 22, 2016
Applicant:
Anamar Ab, Stockholm, SE;
Inventor:
Lars Pettersson, Lund, SE;
Assignee:
ANAMAR AB, Stockholm, SE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/06 (2006.01); C07D 401/04 (2006.01); C07D 403/04 (2006.01); C07D 405/04 (2006.01); C07D 409/04 (2006.01); C07D 231/54 (2006.01); A61P 29/00 (2006.01);
U.S. Cl.
CPC ...
C07D 231/06 (2013.01); A61P 29/00 (2018.01); C07D 231/54 (2013.01); C07D 401/04 (2013.01); C07D 403/04 (2013.01); C07D 405/04 (2013.01); C07D 409/04 (2013.01);
Abstract
Provided are 1-amidino-3-aryl-2-pyrazoline derivatives which exhibit antagonizing activity towards serotonin 5-HT 2B receptors and pharmaceutical compositions containing these derivatives. Also provided is the use of the compounds as a medicament and for the treatment of fibrosis, cardiovascular diseases, pain, IBD, and other inflammatory diseases.