The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 28, 2020

Filed:

Apr. 13, 2017
Applicant:

The Penn State Research Foundation, University Park, PA (US);

Inventors:

Jian Yang, State College, PA (US);

Cheng Dong, State College, PA (US);

Zhiwei Xie, State College, PA (US);

Assignee:

The Penn State Researh Foundation, University Park, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 47/69 (2017.01); A61K 31/437 (2006.01); A61K 47/65 (2017.01); A61K 47/59 (2017.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6901 (2017.08); A61K 31/437 (2013.01); A61K 47/593 (2017.08); A61K 47/65 (2017.08); A61K 47/6937 (2017.08); A61P 35/00 (2018.01);
Abstract

In one aspect, methods of targeted nanoparticle and cell delivery are described herein. In some embodiments, methods described herein comprise coupling nanoparticles and cells to a carrier cell to form a nanoparticle-cell conjugate or cell-cell conjugate, disposing the nanoparticle-cell or cell-cell conjugate in a biological environment, and delivering the nanoparticles and cells to target cells or tissues located within the biological environment. The nanoparticles comprise a biodegradable photoluminescent polymer, and the nanoparticle-cell conjugate is formed using one or more click chemistry reaction products.


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