The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2020
Filed:
Jun. 03, 2016
Applicant:
Los Angeles Biomedical Research Institute AT Harbor-ucla Medical Center, Torrance, CA (US);
Inventor:
Michael R. Yeaman, Redondo Beach, CA (US);
Assignee:
Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); C07K 14/195 (2006.01); A61P 33/06 (2006.01); A61P 31/04 (2006.01); A61K 9/00 (2006.01); A61K 38/00 (2006.01); A61K 31/407 (2006.01); A61K 31/542 (2006.01); A61K 38/12 (2006.01); A61K 31/351 (2006.01); A61K 31/365 (2006.01); A61K 31/4418 (2006.01);
U.S. Cl.
CPC ...
A61K 38/16 (2013.01); A61K 9/0019 (2013.01); A61P 31/04 (2018.01); A61P 33/06 (2018.01); A61K 31/351 (2013.01); A61K 31/365 (2013.01); A61K 31/407 (2013.01); A61K 31/4418 (2013.01); A61K 31/542 (2013.01); A61K 38/12 (2013.01); A61K 2300/00 (2013.01);
Abstract
Antimicrobial peptides, compositions and methods are described that are useful for treating infectious diseases, including those caused by drug resistant Gram-negative bacteria (e.g.,and) and parasite-caused diseases such as malaria. The peptides include a modular kinocidin gamma-core connected directly, or through a short spacer, to a kinocidin C-terminal alpha-helix.