The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 28, 2020

Filed:

Jun. 21, 2017
Applicant:

Ejia Biotechnology Co., Ltd, Taichung, TW;

Inventors:

Hong-Lin Su, Taichung, TW;

Chia-Yu Chang, Yunlin County, TW;

Shiaw-Min Hwang, Hsinchu, TW;

Huai-En Lu, Kaohsiung, TW;

Horng-Jyh Harn, Taipei, TW;

Shinn-Zong Lin, Taichung, TW;

Ping-Shan Lai, Taichung, TW;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/365 (2006.01); A61Q 7/00 (2006.01); A61K 8/49 (2006.01); A61K 36/28 (2006.01); A61K 36/23 (2006.01);
U.S. Cl.
CPC ...
A61K 31/365 (2013.01); A61K 8/4973 (2013.01); A61K 36/23 (2013.01); A61K 36/28 (2013.01); A61Q 7/00 (2013.01); A61K 2800/74 (2013.01);
Abstract

The present invention discloses use of butylidenephthalide (Bdph), a method of using the same, and a method for preparing a pharmaceutical composition containing the same. Because Bdph has the capability of promoting the hair growth and reducing the β-amyloid protein (Aβ) level in nerve cells, the efficacy of improving the health and appearance of a subject can be achieved by administrating an effective amount of Bdph to the subject. Specifically, the Bdph has the efficacy of preventing or treating neurodegenerative diseases such as Alzheimer's disease caused by excessive build up of Aβ in the cells, and as an active ingredient in a topical composition, the Bdph is effective in promoting the hair growth at the site where the Bdph is administered. Furthermore, the method for preparing a pharmaceutical composition containing Bdph comprises preparing the pharmaceutical composition through an organic synthesis reaction, wherein the Bdph is coated with a polymeric material such as F127 by covalent bonding of the polymeric material with the Bdph, thereby achieving the effect of reducing the cytotoxicity of the pharmaceutical composition for an organism.


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