The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2020

Filed:

Aug. 03, 2015
Applicants:

Katholieke Universiteit Leuven, K.u.leuven R&d, Leuven, BE;

Vanderbilt University, Nashville, TN (US);

Inventors:

Richard M. Caprioli, Brentwood, TN (US);

Bart De Moor, Bierbeek, BE;

Raf Van De Plas, Molenbeek-Wersbeek, BE;

Nico Verbeeck, Tremelo, BE;

Etienne Waelkens, Rotselaar, BE;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06K 9/00 (2006.01); H01J 49/00 (2006.01); G06K 9/20 (2006.01); G06K 9/62 (2006.01); G06T 7/00 (2017.01);
U.S. Cl.
CPC ...
G06K 9/00147 (2013.01); G06K 9/2054 (2013.01); G06K 9/6218 (2013.01); G06T 7/0012 (2013.01); H01J 49/0004 (2013.01); G06T 2207/10081 (2013.01); G06T 2207/10116 (2013.01); G06T 2207/10132 (2013.01); G06T 2207/30048 (2013.01);
Abstract

Imaging mass spectrometry (IMS) has become a prime tool for studying the distribution of biomolecules in tissue. Although IMS data sets can become very large, computational methods have made it practically feasible to search these experiments for relevant findings. However, these methods lack access to an important source of information that many human interpretations rely upon: anatomical insight. In this work, this need is addressed by (1) integrating a curated anatomical data source with an empirically acquired IMS data source, establishing an algorithm-accessible link between them; and (2) demonstrating the potential of such an IMS-anatomical atlas link by applying it toward automated anatomical interpretation of ion distributions in tissue.


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