The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2020

Filed:

Jul. 10, 2015
Applicant:

Tetec Tissue Engineering Technologies Ag, Reutlingen, DE;

Inventors:

Karin Benz, Göppingen, DE;

Christian Freudigmann, Reutlingen, DE;

Christoph Gaissmaier, Kusterdingen, DE;

Jochen Hecky, Freiburg, DE;

Jürgen Mollenhauer, Reutlingen, DE;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); C12N 5/077 (2010.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6887 (2013.01); C12N 5/0655 (2013.01); C12Y 304/24007 (2013.01); G01N 2333/78 (2013.01);
Abstract

A method for the in vitro detection of cartilage tissue and/or for the in vitro determination of the purity of cartilage tissue includes: a) treating a tissue sample with a protease and b) testing the protease-treated tissue sample for the presence of protease-resistant fragments of type II collagen and/or type I collagen. Methods can be carried out for preparing a cartilage cell culture, and for preparing a cartilage cell-loaded implant. Protease-resistant fragments of type II collagen and/or type I collagen can be used for the in vitro detection of cartilage tissue and/or for the in vitro determination of the purity of cartilage tissue. A kit can be used for carrying out the methods.


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