The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2020
Filed:
Sep. 18, 2018
Applicant:
National Jewish Health, Denver, CO (US);
Inventor:
Milene Saavedra, Denver, CO (US);
Assignee:
National Jewish Health, Denver, CO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/34 (2006.01); G01N 33/537 (2006.01); C12Q 1/6883 (2018.01); G01N 33/68 (2006.01); G16H 50/30 (2018.01); G16B 40/00 (2019.01); G16C 99/00 (2019.01); G06F 19/00 (2018.01);
U.S. Cl.
CPC ...
G01N 33/537 (2013.01); C12Q 1/6883 (2013.01); G01N 33/68 (2013.01); G01N 33/6893 (2013.01); G06F 19/00 (2013.01); G16B 40/00 (2019.02); G16C 99/00 (2019.02); G16H 50/30 (2018.01); C12Q 2600/118 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/16 (2013.01); G01N 2333/54 (2013.01); G01N 2333/705 (2013.01); G01N 2333/70503 (2013.01); G01N 2333/70535 (2013.01); G01N 2333/70596 (2013.01); G01N 2333/924 (2013.01); G01N 2333/96486 (2013.01); G01N 2400/40 (2013.01); G01N 2800/122 (2013.01); G01N 2800/125 (2013.01); G01N 2800/127 (2013.01); G01N 2800/50 (2013.01);
Abstract
The present invention is related to novel methods for for determining pulmonary disease progression severity in a subject having cystic fibrosis by detecting mRNA expression levels of CD64 in a whole blood sample for the subject and calculating a disease risk score, wherein the disease risk score correlates to the risk score for mild, moderate or severe pulmonary disease progression at exacerbation and treating the subject accordingly.